Associate Director, DMPK/ADME

Job Title: Associate Director, DMPK/ADME
Company: Biopharma
Location: Boston, MA

Brio Resource Group is a Life Sciences Executive Search Firm committed to providing rare talent on an exclusive search basis to the Biopharma, Pharma, Device, and CRO industries. We work on behalf of organizations that value true talent acquisition partners and specialize in supporting emerging Biopharma companies offering life-changing therapies. Our many years of experience, subject matter expertise, comprehensive search process, and genuine passion to deliver rare talent defines Brio.

Position Overview:
We’ve partnered with a rapidly growing biotech company in Boston that’s seeking an Associate Director, DMPK/ADME to support small molecule programs from discovery through early clinical development. This is a critical and strategic role for a scientist eager to guide ADME/DMPK activities and work cross-functionally in a collaborative, innovative environment focused on developing transformative therapies.

Opportunity Highlights:

  • Serve as the DMPK/ADME subject matter expert on cross-functional project teams

  • Design, oversee, and interpret both in vitro and in vivo ADME/DMPK studies

  • Manage relationships and study execution with external CRO partners

  • Lead development of DMPK sections of regulatory filings (INDs, IBs, DSURs)

  • Contribute to the evaluation and implementation of emerging technologies and assays

  • Collaborate closely with Preclinical, Clinical, CMC, and Bioanalytical teams

  • Drive integration of drug metabolism, PK, and drug disposition data into development strategies

  • Help shape internal processes, systems, and guidance for DMPK function expansion

Position Requirements:

  • PhD or PharmD with 6–8 years of relevant industry experience, or BS/MS with 10+ years in drug metabolism, pharmacokinetics, or related fields

  • Demonstrated experience in both hands-on and strategic execution of nonclinical DMPK studies

  • Strong background in outsourcing and CRO management for ADME/PK programs

  • Experience supporting IND-enabling studies and early-phase clinical programs

  • Familiarity with radiolabeled studies and human dosimetry is a plus

  • Prior exposure to CNS therapeutic areas is advantageous

  • Excellent scientific communication skills, both written and verbal

  • Highly collaborative and proactive mindset with strong attention to detail

We welcome the opportunity to provide a full job description upon resume review.