From Outsourced Support to Internal Leadership

A growing biopharmaceutical company wanted greater internal ownership of its global clinical programs. Its priorities were to reduce reliance on CRO outsourcing, strengthen oversight of trial execution and quality, and build an internal clinical operations team.

Brio first filled two Vice President of Clinical Operations positions, establishing the leadership foundation for this transition. We then filled supporting roles across clinical trial administration, clinical trial management, monitoring excellence, and director-level clinical operations.

These hires helped the company bring expertise in-house and build teams around its new leaders, strengthening its capacity to manage global programs with greater control over processes, quality, and execution.

Specialized Talent for a Critical Trial Launch

A clinical-stage oncology biotech developing targeted radiotherapies needed experienced contract CRAs to support site qualification and activation for a Phase 2 prostate cancer trial across the United States. The assignment required professionals who could assess site readiness and navigate the operational demands of oncology studies involving nuclear medicine.

Through our Contract Resourcing solution, Brio engaged its established network of vetted oncology monitoring specialists. Within two days, we introduced six CRA profiles averaging more than 15 years of oncology monitoring experience.

All six candidates advanced to interviews, and the company selected three. The positions were filled within 14 days of introduction, providing experienced clinical monitoring capacity to support site readiness and trial start-up.

A National Search for a Rare Leadership Profile

A clinical-stage biotech developing cancer immunotherapies needed a Chief Medical Officer with an uncommon combination of qualifications: board certification in oncology, immunotherapy clinical development experience, and a track record of bringing therapies to market with commercial success.

The search required more than therapeutic expertise. The company needed a medical leader who could connect clinical development strategy with the longer-term path toward commercialization.

Brio conducted a national search, engaging executives with relevant oncology and immunotherapy backgrounds while assessing alignment with the company’s priorities and openness to relocation.

Over a 90-day period, Brio introduced eight profiles. Six candidates advanced to interviews, three became finalists, and the company selected its CMO. The successful candidate relocated to join the organization, bringing the combination of medical expertise, development experience, and commercial perspective the role demanded.