Vice President, Clinical Development
Vice President, Clinical Development
Company: Commercial-Stage Oncology and Hematology Biopharmaceutical Company
Location: South San Francisco, CA
Employment Type: Permanent
The Opportunity
Brio Resource Group is partnering with a commercial-stage biopharmaceutical company focused on oncology and hematology to identify a Vice President, Clinical Development.
Reporting to the Chief Medical Officer, this executive will provide strategic leadership for clinical development programs and related evidence-generation activities. The successful candidate will shape development strategy, oversee clinical execution, ensure regulatory readiness, and contribute to portfolio-level decisions as the organization advances and expands its therapeutic pipeline.
Key Responsibilities
- Provide executive oversight of clinical development programs across assigned therapeutic areas and assets.
- Develop clinical strategies and development plans aligned with product objectives, registration pathways, and lifecycle priorities.
- Lead the design and execution of Phase I–IV clinical trials, including protocols, endpoints, data analysis, interpretation, and reporting.
- Oversee key clinical documents, including protocols, investigator brochures, clinical study reports, and regulatory submission materials.
- Partner with Clinical Operations and CROs to ensure high-quality trial execution, medical monitoring, data integrity, and regulatory compliance.
- Collaborate closely with Biometrics, Regulatory Affairs, Medical Affairs, Drug Safety, and other cross-functional partners.
- Represent Clinical Development in project teams, portfolio reviews, investment discussions, and governance committees.
- Support global health-authority interactions through strategic input, briefing materials, responses, and clinical data presentations.
- Engage investigators, key opinion leaders, scientific advisors, and advisory boards to inform development strategy.
- Provide clinical and scientific input into business-development diligence, licensing, and partnership opportunities.
- Translate emerging clinical data into actionable recommendations for program and portfolio decisions.
- Partner with the CMO to strengthen clinical-development capabilities, processes, and talent.
Qualifications
- MD or equivalent medical degree with advanced expertise in hematology and/or oncology.
- Board certification in hematology or oncology is preferred.
- At least eight years of clinical research or drug-development experience spanning Phase I–IV programs.
- At least six years of experience within a biotechnology or pharmaceutical company.
- Demonstrated leadership of clinical development strategy and execution within oncology or hematology.
- Experience supporting global health-authority interactions and contributing to regulatory strategy.
- Thorough knowledge of clinical-trial design, statistics, Good Clinical Practice, and regulatory requirements.
- Ability to evaluate and communicate complex scientific and clinical data to guide development and portfolio decisions.
- Proven executive leadership within cross-functional and matrixed organizations.
- Strong relationships with external investigators, scientific experts, and key opinion leaders.
- Exceptional executive communication, presentation, collaboration, and influencing skills.
Why Consider This Opportunity?
This role offers the opportunity to work directly with the Chief Medical Officer, influence clinical and portfolio strategy, and lead the development of meaningful oncology and hematology programs within an established biopharmaceutical organization. The position includes a competitive executive compensation package with base salary, annual bonus, equity incentives, and comprehensive benefits.
We will provide a complete job description and additional company information after an initial résumé review.
